Publications

My research spans human microbiome biology, therapeutic discovery, environmental genomics, and computational methods for studying complex biological systems. Across 20+ peer-reviewed publications, I have helped investigate how microbial communities shape human health, recover previously uncharacterized organisms and biological systems, and translate large-scale genomic data into experimentally actionable findings.

My work includes publications in Cell, Nature, Science, Nature Communications, The ISME Journal, and Environmental Microbiology.

Selected recent and high-impact publications

Human microbiome, immunology, and therapeutics

• Discovery and engineering of the antibody response to a prominent skin commensal. Nature 638, 1054–1064 (2025). Google Scholar

• Randomly barcoded transposon mutant libraries for gut commensals I: Strategies for efficient library construction. Cell Reports 43 (2024). Google Scholar

• Strain dropouts reveal interactions that govern the metabolic output of the gut microbiome. Wang, Osborn, Jain, et al. Cell 186, 2839–2852.e21 (2023). Google Scholar

• Ultra-deep sequencing of Hadza hunter-gatherers recovers vanishing gut microbes. Carter et al., including Jain. Cell 186, 3111–3124.e13 (2023). Google Scholar

• Mapping the T cell repertoire to a complex gut bacterial community. Nagashima et al., including Jain. Nature 621, 162–170 (2023). Google Scholar

• Design, construction, and in vivo augmentation of a complex gut microbiome. Cheng, Ho, Aranda-Díaz, Jain, et al. Cell 185, 3617–3636.e19 (2022). Google Scholar

• Robust variation in infant gut microbiome assembly across a spectrum of lifestyles. Olm, Dahan, et al., Jain. Science 376, 1220–1223 (2022). Google Scholar

Environmental genomics and natural-product discovery

• Identification and analysis of the bacterial endosymbiont specialized for production of the chemotherapeutic natural product ET-743. Schofield* and Jain* et al. Environmental Microbiology 17, 3964–3975 (2015). Co-first authors. DOI

• Genomic and transcriptomic evidence for scavenging of diverse organic compounds by widespread deep-sea archaea. Li, Baker, Anantharaman, Jain, Breier, and Dick. Nature Communications 6, 8933 (2015). DOI

• Metabolic flexibility of enigmatic SAR324 revealed through metagenomics and metatranscriptomics. Sheik, Jain, and Dick. Environmental Microbiology 16, 304–317 (2014). DOI

• The metatranscriptome of a deep-sea hydrothermal plume is dominated by water-column methanotrophs and lithotrophs. Lesniewski, Jain, Anantharaman, Schloss, and Dick. The ISME Journal 6, 2257–2268 (2012). DOI

For the complete and most current publication list, citation counts, and co-author information, visit my 

Google Scholar profile